It should not be possible to have a zany subplot teaming up Delroy Lindo and Holly Hunter that through its tonal dissonance continually threatens to bring a movie to a screeching halt, but Danny Boyle found a way to do it.
And that direct-address two-shot featuring the leads saying the quiet parts out loud while a montage of scenes from the movie runs behind them is a very serious contender for all-time worst near-final shot.